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With this ICMS autumn newsletter we inform you about the progress we made together these last months.
This year we can finally meet each other in real live. During the ICMS event on December 2 we will build our growing community further. During this 2nd annual event of ICMS we will launch our ICMS movie, professor Theo Mulder will give his integrated vision on the Human Motor system, you will learn more about our great facilities and our medical technological oriented research on different patient journeys (i.e. orthopedic, reumatologic and neurological patients).
For our 1st Best ICMS Poster Award contest we invite you all to submit a poster of your research on patients with postural and movement disorders and associated technologies in order for everyone to become aware of the important research we are performing together.
The full program will follow on short notice as well as registration options.
Involving patients and citizens in research is important for ICMS and initiatives to achieve this have been taken by Christiane Grünloh (Roessingh Research en Development) , Ria Wolkorte (Universiteit Twente) and Rita Schriemer (Sint Maartenskliniek / Radboudumc). Together they can make research more relevant and better. And beyond that, patient participation, citizen science and human-centered design keep the conversations between science and society going.
Interested in more? They wrote an article.
And some of our research leads published a research article in BMC Rheumatology on patient involvement in research: to the article.
In her inaugural speech called Stepwise, on September 16, 2022, Professor Vivian Weerdesteyn clarified the contents of her chair on Motor Control and Rehabilitation at the Radboud University / Faculty of Medical Sciences. Vivian will focus on investigating mechanisms that may lead to a decrease of mobility problems, and the translation of this knowledge into new and better treatment. During her PhD she already developed the successful 'Vallen Verleden Tijd' program. In her current role, she will start new research projects and supervises PhD students working on these projects. This also applies to the program Topspecialische Zorg & Onderzoek (TZO) granted to the Sint Maartenskliniek. Four studies within this program will take place at the Loop Expertise Centrum (LEC). The LEC is focused on improving diagnostics and treatment of people with complex neurological walking problems.
The speech has been recorder and can be watched back here.
During this fully booked symposium on September 30th several ICMS Clinical Research Leads and Research Leads contributed:
After this plenary programme there was the opportunity to see demonstrations on the Grail, Zero-G, C-mill, Lokomat and the gaitlab in the Loop Expertise Centrum (LEC)
ICMS Research Lead Nico Verdonschot showed the Dynamic imaging and modeling of the lower extremity for the benefit of orthopedic patients. In his lecture he expressed his fascination for new possibilities of looking inside the body with various scanning modalities (X-ray, CT, MRI, ultrasound) to assess the status of the musculoskeletal system (bone quality, joint condition, implant related issues). It is even possible to generate these images during motion (typically within a scanning environment). This allows for a better understanding of the dynamical aspects of the musculoskeletal system and typically provide much more information about pathologies and how these pathologies should be solved. In addition, these dynamical examinations can be coupled with computer models (e.g. finite element models combined with musculoskeletal models) allowing for predictions and optimalisation of interventions.
The presentation highlighted some examples where we have been successful in the development of specific workflows to test implants for manufacturers, develop implants, and utilize personalized models for the benefit of our patients.
ICMS Research Lead Nico Verdonschot showed the Dynamic imaging and modeling of the lower extremity for the benefit of orthopedic patients. In his lecture he expressed his fascination for new possibilities of looking inside the body with various scanning modalities (X-ray, CT, MRI, ultrasound) to assess the status of the musculoskeletal system (bone quality, joint condition, implant related issues). It is even possible to generate these images during motion (typically within a scanning environment). This allows for a better understanding of the dynamical aspects of the musculoskeletal system and typically provide much more information about pathologies and how these pathologies should be solved. In addition, these dynamical examinations can be coupled with computer models (e.g. finite element models combined with musculoskeletal models) allowing for predictions and optimalisation of interventions.
The presentation highlighted some examples where we have been successful in the development of specific workflows to test implants for manufacturers, develop implants, and utilize personalized models for the benefit of our patients.
Did you mis the lecture? You can watch is back here: Third ICMS lecture
FOREUM CALL FOR RESEARCH PROPOSALS ON E-HEALTH
While promising and exciting, there are enormous challenges to ensure that E-health makes health care more efficient and more responsive to people's needs and expectations, for instance due to unequal access to the use of technology.
FOREUM Foundation for Research in Rheumatology seeks to support projects that focus on stimulating application-driven research and innovations that allow to improve both individual and population health of people living with rheumatic and musculoskeletal disorders (RMDs) (for instance via personalized treatment approaches).
They call for projects that aim to help those living with RMDs to
More information: https://www.foreum.org/call_open_for_application.cfm
INNOVATIVE HEALTH INITIATVE (IHI)
IHI calls for proposals represent an opportunity for organisations involved in health research and healthcare to form consortia and apply to be part of cross-sector partnerships that bring together a range of stakeholders to tackle some of the biggest challenges in health research today.
The draft topics for IHI calls 3 have recently been published:
https://www.ihi.europa.eu/apply-funding/future-opportunities
Precautions following total hip arthroplasty
Anil Peters-Veluthamaningal
Total hip arthroplasty (THA) is one of the most successful and frequently undertaken elective surgeries. The posterolateral approach, the most frequently used surgical approach to a THA in the Netherlands and worldwide, is thought to have a higher risk of dislocation than other approaches. Postoperative precautions following THA are traditionally prescribed to ensure appropriate healing and prevent early postoperative dislocation.
The thesis of Anil aims to contribute to optimizing the set of postoperative precautions following posterolateral THA by generating knowledge regarding current practice, compliance, and burden, as well as effectiveness. In conclusion, considerable heterogeneity in the prescribed precautions is considered. Compliance with movement restrictions is higher than with functional restrictions. The burden of sleeping restrictions is high, and these restrictions can be effectively removed without increasing the risk of dislocation. Optimizing the set of postoperative precautions following posterolateral THA will create opportunities for more personalized care.
Anil Peters-Veluthamaningal is a PhD student in the research group Biomedical Signals and Systems. Supervisor is prof.dr. M.M.R. Vollenbroek - Hutten and co-supervisor is dr. M.H.A. Huis in 't Veld.
Meet my HUBBI: he’s an expert in ehealth usability
Marijke Broekhuis
Establishing proper usability is like finding the right person to marry. You want a person that is compatible with you. Someone who acknowledges your needs, you enjoy being around with, you easily get along with, and ‘fits’ within your world of people you hold dear. With usability, it is not that much different. The system should be compatible with its intended users by addressing their needs, making sure that they like to use the system, making it easy to use the system and fitting the system within the intended use context.
In this thesis, Marijke focused on: how to (1) include usability within the development process of eHealth and (2) improve usability benchmarking for eHealth services. Within the second part, she describe the development and validation of a new usability benchmarking tool for eHealth: the eHealth UsaBility Benchmarking Instrument (HUBBI).
Marijke is a PhD student in the research group Biomedical Signals and Systems. Supervisor is ICMS Research Lead prof.dr.ir. H.J. Hermens from the Faculty of Electrical Engineering, Mathematics and Computer Science and co-supervisor is dr. L.S. van Velsen from the Faculty of Behavioural, Management and Social Sciences.
Functional assistive devices to support the impaired shoulder and hand
Claudia Haarman
To be able to independently perform daily activities, it is important that humans can use their arms and hands to a sufficient extent. The positioning of the arm and the execution of grasping tasks play an essential role in this. Disability caused by impairments of arm and hand function can lead to activity limitations and participation restrictions.
Assistive devices can contribute to reducing the effect of disability. However, these devices must meet users’ expectations regarding effectiveness, reliability, durability, comfort and ease of use to reduce the risk of device abandonment. In this thesis Claudia developed and evaluated three novel assistive devices that support patients with impaired shoulders or hands. During the design process she focused on restoring performance (i.e. on the activity and participation level) rather than restoring capacity (i.e. on the impairment level). Therefore, all device functionality that did not contribute to this goal was omitted from the design.
In conclusion, the work presented in this thesis showed the significant steps that were made in improving assistive devices to support shoulder and hand function during daily activities.
Claudia Haarman is a PhD student in the research group Biomechanical Engineering. Supervisors are ICMS Research Lead prof.dr.ir. H. van der Kooij and Clinical Research Lead prof.dr. J.S. Rietman from the Faculty of Engineering Technology.
Going off-road, Exploring and mapping psoriatic arthritis
Mlichelle Mulder
Little research has been done on the diagnosis and treatment of psoriatic arthritis (PsA). For a long time it was lumped together with rheumatoid arthritis (RA). The disease is still occasionally overlooked by dermatologists and primary care physicians. You can see this in the doctor's office: sometimes there is already damage to the joints before the patient sees the rheumatologist. The need for more knowledge on this subject was so great that the regional promotion fund rewarded the research proposal in this area of the Radboudumc and the Sint Maartenskliniek with a grant in 2017.
Michelle's PhD research delivers immediate improvements to the care of PsA patients. It starts with the diagnosis. It turns out that we can most likely distinguish psoriasis and psoriatic arthritis patients from each other using machine learning (a form of artificial intelligence) and mapping immune cell profiles. This can help in the early detection of PsA in psoriasis patients.
In addition, the study focused on monitoring the disease activity of PsA patients. Until recently, the disease activity measured in the same way as in patients with RA. The results of a tailor-made, PsA-focused method proved to be more reliable and complete. This new method of measurement was immediately applied in our patient care.
The research on wearable motion sensors got great attention during the Nijmegen Four Days Marches as a trial to test whether the sensors are able to provide valuable information about how patients walk in daily life. Measurements in the hospital do not provide an adequate picture of walking in daily life therefor in the future we intent to bring motion sensors into the homes of patients. During the research the sensors provided approximately 150 hours of walking data. They measured important data for each step, including: stride length, symmetry, stability and walking speed. The image shows how detailed the sensors map information about walking
November 11, 2022: Verder in Beweging
https://verderinbeweging.nl/
December 2, 2022: Annual ICMS event
December, 8 Mini symposium 'Moving forward' Technological Developments in Rehabilitation. With special guest Dr. Levi Hargrove from Shirley Ryan Ability Lab in Chicago and from 14.30 on PhD defense of Robert Schulte. University of Twente
March 31, 2022: Inaugural lecture Professor Noël Keijsers
April 13-14, 2023: International RSA meeting
https://meeting2023.radiostereometry.org
ek.org/